Increased atherosclerotic plaque burden after intravascular radiation in an atherosclerotic rabbit model

Smoking in Relation to Coronary Atherosclerotic Plaque Burden, Volume and Composition on Intravascular Ultrasound

BACKGROUND This study aimed to evaluate the relationship between cigarette smoking and coronary atherosclerotic burden, volume and composition as determined in-vivo by grayscale and virtual histology (VH) intravascular ultrasound (IVUS). METHODS AND RESULTS Between 2008 and 2011, (VH-)IVUS of a non-culprit coronary artery was performed in 581 patients undergoing coronary angiography. To accou...

Intravascular ultrasound-derived measures of coronary atherosclerotic plaque burden and clinical outcome.

OBJECTIVES The aim of this study was to investigate the relationship between intravascular ultrasound (IVUS)-derived measures of atherosclerosis and cardiovascular outcomes. BACKGROUND IVUS has been used in clinical trials to evaluate the effect of medical therapies on coronary atheroma progression. METHODS Coronary plaque progression was evaluated in 4,137 patients in 6 clinical trials tha...

Atherosclerotic plaque rupture: an overview

Renal artery atherosclerotic plaque ruptures visualised with intravascular ultrasound.

Renal angiography frequently yields indeterminate results (particularly in aneurysms), that in coronaries were found to be plaque rupture sites. In this setting, use of intravascular ultrasound (IVUS) allows unique insights into actual lesion anatomy. We present three cases with striking in-vivo IVUS visualisation of renal artery atherosclerotic plaque rupture. Panels A, B, and C show three dis...

Intravascular magnetic resonance imaging of aortic atherosclerotic plaque composition.

Magnetic resonance imaging (MRI) may be an excellent tool to define atherosclerotic plaque composition, but surface MRI (SMRI) suffers from a low signal-to-noise ratio and low resolution of arterial images. Intravascular MRI (IVMRI) represents a potential solution for acquiring high-quality in vivo images of atherosclerotic plaques. Isolated segments of 11 thoracic human aortas obtained at auto...